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Invitrogen™ TRAF7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA141285

Catalog No. 01-675-626


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Description

Description

Suggested positive control: antigen standard for TRAF7 (transient overexpression lysate).

TRAFs are signal transducers for members of TNFR superfamily. These are critically involved in activation of MAP3K family members involved in NF-kappaB and JNK activation and apoptosis. TRAF7, a novel 670 A. A protein, is a human homolog of mouse Traf7 andconsists of an N-terminal RING finger domain, central TRAF domain, a coiled-coil motif and 7 WD40 repeats at the C-terminus. It has E3-ubiquitin ligase activity for self-ubiquitination. TRAF7 specifically interacts with MEKK3 and mediates MEKK3-induced AP1 and CHOP activation and induces apoptosis through Caspase-independent pathways. It is a multifunctional protein involved in sumoylation and negative regulation of c-Myb, thereby regulating proliferation and differentiation of hematopoietic cells.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TRAF7
Polyclonal
Unconjugated
TRAF7
DKFZp586I021; E3 ubiquitin-protein ligase TRAF7; MGC7807; RFWD1; RGD1559653; ring finger and WD repeat domain 1; ring finger and WD repeat domain 1 isoform 1; RING finger and WD repeat-containing protein 1; RING finger protein 119; RING-type E3 ubiquitin transferase TRAF7; RNF119; TNF receptor associated factor 7; TNF receptor-associated factor 7; TNF receptor-associated factor 7, E3 ubiquitin protein ligase; traf7
Rabbit
Protein G
RUO
100065698, 224619, 360491, 84231
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunoprecipitation, Western Blot
1.0 mg/mL
PBS with 0.05% sodium azide
Q6Q0C0, Q922B6
TRAF7
Synthetic peptide corresponding to residues 334-356 of humanTRAF7.
100 μg
Primary
Human, Mouse, Rat, Horse
Antibody
IgG
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