trans-4-Hydroxy-L-proline, 99+%, Thermo Scientific Chemicals

Description

 

trans-4-Hydroxy-L-proline is used as a reagent for the preparation of neuroexcitatory kainoids and antifungal echinocandins. It is also involved in the synthesis of chiral ligands for enantioselective ethylation of aldehydes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
trans-4-Hydroxy-L-proline is used as a reagent for the preparation of neuroexcitatory kainoids and antifungal echinocandins. It is also involved in the synthesis of chiral ligands for enantioselective ethylation of aldehydes.

Solubility
Soluble in water.

Notes
Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 51-35-4
• Molecular Formula: C5H9NO3
• Molecular Weight (g/mol): 131.131
• MDL Number: MFCD00064320
• InChI Key: PMMYEEVYMWASQN-DMTCNVIQSA-N
• Synonym: trans-4-hydroxy-l-proline, hydroxyproline, l-hydroxyproline, 2s,4r-4-hydroxypyrrolidine-2-carboxylic acid, 4-hydroxy-l-proline, l-4-hydroxyproline, hydroxy-l-proline, trans-4-hydroxyproline, h-hyp-oh, hypro
• PubChem CID: 5810
• ChEBI: CHEBI:18095
• IUPAC Name: (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid
• SMILES: C1C(CNC1C(=O)O)O

• Melting Point: 270°C to 273°C (decomposition)
• Beilstein: 471933
• Merck Index: 14,4840
• Solubility Information: Soluble in water.
• Quantity: 25 g
• Optical Rotation: −76° (c=4 in water)
• Formula Weight: 131.13
• Percent Purity: ≥99%
• Chemical Name or Material: trans-4-Hydroxy-L-proline

Safety and Handling

EINECSNumber	200-091-9
RTECSNumber	TW3586500
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only