Invitrogen™ Transferrin Monoclonal Antibody (HTF-14)

Catalog No.	Quantity
01-674-986	100 μg

Catalog No. 01-674-986 Supplier Invitrogen™ Supplier No. MA119013

Description

Mouse Monoclonal Antibody

This antibody recognizes an epitope located in the N-terminal domain of human serum transferrin, a 77 kDa single polypeptide chain glycoprotein (member of the iron binding family of proteins). It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. This antibody will not cross-react with sheep, canine, equine or bovine. A suggested positive control is placental tissue. Western Blot: non-reducing conditions; Functional Application: Blocking.

Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis.Serum transferrin may also have a further role in stimulating cell proliferation.

Specifications

• Antigen: Transferrin
• Applications: ELISA, Functional Assay, Immunohistochemistry (Paraffin), Radioimmune Assays (RIA), Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: HTF-14
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.4
• Gene: Tf
• Gene Accession No.: P02787, P09571, P19134, Q29545
• Gene Alias: AI266983; beta-1 metal-binding globulin; Cd176; DKFZp781D0156; epididymis secretory sperm binding protein Li 71p; HEL-S-71p; HP; hpx; hypotransferrinemia with hemochromatosis; ICA; Inhibitor of carbonic anhydrase; lactoferrin; liver regeneration-related protein LRRG03; liver transferrin; LOC100146633; PICA; porcine inhibitor of carbonic anhydrase; porcine inhibitor of carbonic anhydrase precursor; PRO1400; PRO1557; PRO2086; Serotransferrin; siderophilin; TF; Tfn; TFQTL1; transferin; Transferrin; transferrin precursor; Trf
• Gene Symbols: Tf
• Host Species: Mouse
• Immunogen: Purified pig transferrin.
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100009267, 396845, 396996, 7018
• Target Species: Human, Rabbit, Pig
• Content And Storage: 4°C, do not freeze
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1