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Invitrogen™ Transferrin Receptor Monoclonal Antibody (OX-26), FITC
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Catalog No. p-7179155
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PIMA517558 100 μg
PIMA517559 500 μg
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Catalog No. PIMA517558 Supplier Invitrogen™ Supplier No. MA517558
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Description

Mouse Monoclonal Antibody

Transferrin Receptor Monoclonal Antibody for Flow

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Transferrin Receptor
Applications Flow Cytometry
Classification Monoclonal
Clone OX-26
Concentration 0.1 mg/mL
Conjugate FITC
Formulation PBS with 4-5mg/mL BSA and 0.02% sodium azide
Gene TFRC
Gene Accession No. Q99376
Gene Alias 2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Gene Symbols TFRC
Host Species Mouse
Immunogen PHA activated lymph node cells of a PVG rat.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64678
Target Species Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Product Type Antibody
Form Liquid
Isotype IgG2a
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