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Invitrogen™ Transferrin Receptor Monoclonal Antibody (T56/14), PE

Catalog No. MHCD71044
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500 μL
2 mL
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Catalog No. Quantity
MHCD71044 2 mL
50-113-7512 500 μL
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Catalog No. MHCD71044 Supplier Invitrogen™ Supplier No. MHCD71044
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Description

Mouse Monoclonal Antibody

R-phycoerythrin (PE) is a stable and highly soluble phycobiliprotein which provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thus providing an exceptional quantum yields and molar extinction coefficients.

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Transferrin Receptor
Applications Flow Cytometry
Classification Monoclonal
Clone T56/14
Conjugate PE
Formulation PBS with 4mg/mL BSA, sucrose and 0.1% sodium azide
Gene TFRC
Gene Accession No. P02786
Gene Alias 2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Gene Symbols TFRC
Host Species Mouse
Immunogen Human CD71.
Purification Method Purified
Quantity 2 mL
Regulatory Status ASR
Primary or Secondary Primary
Gene ID (Entrez) 7037
Target Species Human
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1
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