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Invitrogen™ Transthyretin Polyclonal Antibody
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Catalog No. PIPA5110655 Shop All Thermo Scientific Products
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PIPA5110655 100 μL
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Catalog No. PIPA5110655 Supplier Invitrogen™ Supplier No. PA5110655
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GTGESKCPLM VKVLDAVRGS PAINVAVHVF RKAADDTWEP FASGKTSESG ELHGLTTEEE FVEGIYKVEI DTKSYWKALG ISPFHEHAEV VFTANDSGPR RYTIAALLSP YSYSTTAVVT NPKE Highest antigen sequence indentity to the following orthologs: Mouse - 81%, Rat - 83%.

Transthyretin (TTR), generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Transthyretin
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.20 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TTR
Gene Accession No. P02766
Gene Alias AA408768; AI787086; Amyloidosis I; ATTR; carpal tunnel syndrome 1; CTS; CTS1; D17860; epididymis luminal protein 111; HEL111; HsT2651; Lr1; PALB; prealbumin; pre-albumin; prealbumin, amyloidosis type I; Tbpa; thyroxine-binding prealbumin; transthyretin; Tt; TTR
Gene Symbols TTR
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human Transthyretin. Recombinant protein control fragment (Product #RP-94759).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7276
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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