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CPC Scientific H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-NH2 (trifluoroacetate salt) 1MG

Supplier: CPC Scientific PARP023A

This peptide can inhibit monocyte spreading on fibronectin-coated slides. The rapidly induced withdrawal of pseudopodial processes and rounding of the cells is accompanied by nitric oxide and endothelin-1 release. Spreading might be inhibited by autocrine endothelin-1 release and subsequent endothelin B receptor-dependent nitric oxide productionONE-LETTER SEQUENCE: SFLLRNPNDKYEPF-NH2MOLECULAR FORMULA: C81H119N21O22MOLECULAR WEIGHT:1738.96STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [141923-36-6], RESEARCH AREA: HematologyREFERENCES: K.D.Srivastava and H.I.Magazine, J. Immunol., 161, 5039 (1998); J.R. Ngaiza and E.A. Jaffe, Biochem. Biophys. Res. Commun., 179, 1656 (1991); D.M. Feng, D.F. Veber, T.M. Connolly, C. Condra, M.J. Tang, and R.F. Nutt, J. Med. Chem.,38,4125 (1995)
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