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TREM-1 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA587413
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100 μL
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PIPA587413 100 μL
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Catalog No. PIPA587413 Supplier Thermo Scientific Supplier No. PA587413

Description

Rabbit Polyclonal Antibody

Positive Samples: HL-60; Cellular Location: Cell membrane, Single-pass type I membrane protein Immunogen sequence: ATKLTEEKYE LKEGQTLDVK CDYTLEKFAS SQKAWQIIRD GEMPKTLACT ERPSKNSHPV QVGRIILEDY HDHGLLRVRM VNLQVEDSGL YQCVIYQPPK EPHMLFDRIR LVVTKGFSGT PGSNENSTQN VYKIPPTTTK ALCPLYTSPR TVTQAPPKST ADVSTPDSEI NLTNVTDIIR VPVFN

TREM1 (triggering receptor expressed on myeloid cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. It is thought that TREM1 other related TREM proteins such as TREM2 act to modulate the inflammatory response. TREM1 has also been linked to inflammatory bowel disease resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TREM-1
Applications Western Blot
Classification Polyclonal
Concentration 5.89 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene TREM1
Gene Accession No. Q9NP99
Gene Alias CD354, sCD354, soluble CD354, soluble TREM 1, soluble TREM1, sTREM 1, sTREM1, TREM, Trem1, TREM-1, triggering receptor expressed in monocytes 1, triggering receptor expressed on monocytes 1, Triggering receptor expressed on myeloid cells, Triggering receptor expressed on myeloid cells 1
Gene Symbols TREM1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 21-205 of human TREM1 (NP_0611131)
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54210
Target Species Human, Rat
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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