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Invitrogen™ TREM1 Monoclonal Antibody (6B1)
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Catalog No. FERMA549133
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100 μg
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Catalog No. Quantity
FERMA549133 100 μg
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Catalog No. FERMA549133 Supplier Invitrogen™ Supplier No. MA549133
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Description

Mouse Monoclonal Antibody

The monoclonal antibody 6B1 recognizes both membrane bound and soluble TREM-1. Also, the monoclonal antibody 6B1 neutralizes the interaction between TREM-1 and its ligand.

TREM1 (triggering receptor expressed on myeloid cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. It is thought that TREM1 other related TREM proteins such as TREM2 act to modulate the inflammatory response. TREM1 has also been linked to inflammatory bowel disease resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.
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Specifications

Antigen TREM1
Applications Flow Cytometry, Functional Assay, Western Blot, Western Blot
Classification Monoclonal
Clone 6B1
Concentration 100 μg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA and no preservative
Gene TREM1
Gene Accession No. Q9NP99
Gene Alias CD354; sCD354; soluble CD354; soluble TREM 1; soluble TREM1; sTREM 1; sTREM1; TREM; Trem1; TREM-1; triggering receptor expressed in monocytes 1; triggering receptor expressed on monocytes 1; Triggering receptor expressed on myeloid cells; Triggering receptor expressed on myeloid cells 1
Gene Symbols TREM1
Host Species Mouse
Immunogen Recombinant TREM-1 - IgG1 fusion protein.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54210
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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