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Invitrogen™ TREM2 Polyclonal Antibody
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Catalog No. PIPA546978 Shop All Thermo Scientific Products
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PIPA546978 100 μg
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Catalog No. PIPA546978 Supplier Invitrogen™ Supplier No. PA546978
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Sheep Polyclonal Antibody

In direct ELISAs, approximately 30% cross-reactivity with recombinant human TREM-2 is observed and less than 1% cross-reactivity with recombinant mouse (rm) TREM-1 and rmTREM-3 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

TREM2 is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).
TRUSTED_SUSTAINABILITY

Specifications

Antigen TREM2
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Trem2
Gene Accession No. Q99NH8
Gene Alias OTTHUMP00000039771; soluble TREM 2; soluble TREM2; sTREM 2; sTREM2; TREM; Trem2; TREM-2; Trem2a; Trem2b; Trem2c; Triggering receptor expressed on monocytes 2; Triggering receptor expressed on myeloid cells; triggering receptor expressed on myeloid cells 2; triggering receptor expressed on myeloid cells 2a; triggering receptor expressed on myeloid cells 2b; triggering receptor expressed on myeloid cells 2c
Gene Symbols Trem2
Host Species Sheep
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse TREM-2b Leu19-Pro168.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 83433
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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