Invitrogen™ H4K20me3 Polyclonal Antibody

Catalog No.	Quantity
PIPA585527	100 μL

Catalog No. PIPA585527 Supplier Invitrogen™ Supplier No. PA585527

Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (100%), Xenopus laevis (100%). Positive Control: HeLa, HeLa nuclear. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: H4K20me3
• Applications: Dot Blot, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene: H4C1
• Gene Accession No.: P62805, P62806
• Gene Alias: CELE_T10C6.11; F07B7.11; F07B7.4; F45F2.12; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4 K20; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/j; H4/K; H4/M; H4/n; H4/O; H4/p; H4-12; H4-16; H4-53; H4C1; H4c11; H4C12; H4C13; H4c14; H4C15; H4C2; H4C3; H4C4; H4C5; H4c6; H4C8; H4C9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K20; H4Lys20me3; H4M; his-20; his-22; his-4; his-52; his-54; his-8; HIST1H4; HIST1H4A; HIST1H4B; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; Hist1h4h; Hist1h4i; HIST1H4J; HIST1H4K; HIST1H4L; Hist1h4m; Hist2h4; HIST2H4A; HIST2H4B; Hist4h4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone cluster 2, H4; histone cluster 2, H4a; Histone Cluster 4; histone cluster 4, H4; histone family member; Histone H2B 2; Histone H4; Histone H4A; Histone H4K20me3; histone IV, family 2; K06C4.12; K06C4.4; methyl Histone 3; methyl Histone H3; T10C6.11; Trimethyl H4; Tri-methyl H4; Trimethyl Histone H4; Tri-methyl Histone H4; Tri-Methyl-H4 K20; Tri-Methyl-H4 Lys20; Tri-Methyl-Histone H4 K20; Tri-Methyl-Histone H4 Lys20; X04652
• Gene Symbols: H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9
• Host Species: Rabbit
• Immunogen: Carrier-protein conjugated synthetic peptide surrounding tri-methyl Lys20 of human Histone H4. The exact sequence is proprietary.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 121504, 319158, 326619, 326620, 8294, 8359, 8363, 8366, 8367, 8370, 97122
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG