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TRIB3 Mouse anti-Human, Clone: OTI3F3, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526897

Catalog No. PIMA526897


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Description

Description

A novel inhibitor of cell division, Tribbles, blocks mitosis at a critical point in Drosophila morphogenesis. Recently, mammalian homologues of Tribbles (Trbs) have been identified that control mitogen-activated protein kinase (MAPK) activity. TRIB3 also known as TRB-3, SINK, and SKIP3 is a member of Trbs family. Overexpression of this protein inhibits NF-kB-dependent transcription induced by tumor necrosis factor (TNF) stimulation or its downstream signaling proteins but does not inhibit NF-kB translocation to the nucleus and binding to DNA. TRIB3/SKIP3 is also overexpressed in multiple human tumors and is regulated by hypoxia.
Specifications

Specifications

TRIB3
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q96RU7
C20orf97, NIPK, SINK, SKIP3, TRB3, TRB-3, neuronal cell death inducible putative kinase, neuronal cell death-inducible putative kinase, p65-interacting inhibitor of NF-kappa-B, p65-interacting inhibitor of NF-kappaB, tribbles homolog 3
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
57761
Immunohistochemistry (Paraffin), Western Blot
OTI3F3
Unconjugated
TRIB3
Liquid
TRIB3
Human recombit protein fragment corresponding to amino acids 1-200 of TRIB3 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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