Triethyl 2-phosphonobutyrate, 97%

Description

CAS: 17145-91-4 | C10H21O5P | 252.247 g/mol

Reactant used for preparation of furospinosulin-1 and analogs as hypoxia-selective antitumor agents, Aminoquinolines as beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors and potential anti-Alzheimer?s drugs, phenylpropanoic acid peroxisome proliferator-activated receptor (PPAR) α-selective agonists as nonalcoholic steatohepatitis (NASH)-preventive agents, PPAR agonists with phenethylphenylphthalimide skeleton derived from thalidomide-related LXR antagonists, notch-sparing γ-secretase inhibitors derived from PPAR agonist library and plakotenin via Diels-Alder reaction, as a potential anticancer agent, naturally found in Okinawan sponge of the genus Plakortis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Reactant used for preparation of furospinosulin-1 and analogs as hypoxia-selective antitumor agents, Aminoquinolines as beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors and potential anti-Alzheimer′s drugs, phenylpropanoic acid peroxisome proliferator-activated receptor (PPAR) α-selective agonists as nonalcoholic steatohepatitis (NASH)-preventive agents, PPAR agonists with phenethylphenylphthalimide skeleton derived from thalidomide-related LXR antagonists, notch-sparing γ-secretase inhibitors derived from PPAR agonist library and plakotenin via Diels-Alder reaction, as a potential anticancer agent, naturally found in Okinawan sponge of the genus Plakortis.

Solubility
Not miscible or difficult to mix with water.

Notes
Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Specifications

Chemical Identifiers

• CAS: 17145-91-4
• Molecular Formula: C10H21O5P
• Molecular Weight (g/mol): 252.247
• MDL Number: MFCD00041347
• InChI Key: GYUCVQSNZFRDRL-UHFFFAOYSA-N
• Synonym: triethyl 2-phosphonobutyrate, ethyl 2-diethoxyphosphoryl butanoate, ethyl 2-diethylphosphono butyrate, butanoic acid, 2-diethoxyphosphinyl-, ethyl ester, triethyl 2-phosphonobutanoate, .alpha.-diethylphosphono butanoic acid, ethyl ester, butyric acid, 2-phosphono-, triethyl ester, butyric acid, triethyl ester, triethyl 2-phosphonobu-tyrate, triethyl-2-phosphono butyrate
• PubChem CID: 229053
• IUPAC Name: ethyl 2-diethoxyphosphorylbutanoate
• SMILES: CCC(C(=O)OCC)P(=O)(OCC)OCC

• Density: 1.064
• Boiling Point: 105°C to 106°C (2 mmHg)
• Flash Point: >110°C (230°F)
• Refractive Index: 1.433
• Quantity: 5 g
• Beilstein: 1789280
• Solubility Information: Not miscible or difficult to mix with water.
• Formula Weight: 252.25
• Percent Purity: 97%
• Chemical Name or Material: Triethyl 2-phosphonobutyrate

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319 Causes skin irritation. Causes serious eye irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only