Triethyl orthopropionate, 97%

Description

CAS: 115-80-0 | C9H20O3 | 176.26 g/mol

Used as intermediates in pharmaceutical chemical and organic synthesize. It can react with N-benzoyl-glycine in the presence of 4-(dimethylamino)pyridine and acetic anhydride to produce 4-(1-ethoxy-propylidene)-2-phenyl-4H-oxazol-5-one. It is also applied as a starting material in the synthesis of Triethyl orthoacrylate. Triethyl orthopropionate is also commonly used in Claisen rearrangement reactions that yield γ,δ-unsaturated esters.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Used as intermediates in pharmaceutical chemical and organic synthesize. It can react with N-benzoyl-glycine in the presence of 4-(dimethylamino)pyridine and acetic anhydride to produce 4-(1-ethoxy-propylidene)-2-phenyl-4H-oxazol-5-one. It is also applied as a starting material in the synthesis of Triethyl orthoacrylate. Triethyl orthopropionate is also commonly used in Claisen rearrangement reactions that yield γ,δ-unsaturated esters.

Solubility
Hydrolyzes slowly in water. Soluble in alcohol, chloroform, ethyl acetate and ether.

Notes
Store away from water/moisture and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Protect against electrostatic charges. Keep ignition sources away.

Specifications

Chemical Identifiers

• CAS: 115-80-0
• Molecular Formula: C9H20O3
• Molecular Weight (g/mol): 176.26
• MDL Number: MFCD00009226
• InChI Key: FGWYWKIOMUZSQF-UHFFFAOYSA-N
• Synonym: triethyl orthopropionate, ethyl orthopropionate, propane, 1,1,1-triethoxy, triethylorthopropionate, triethyl o-propionate, orthopropionic acid ethyl ester, orthopropionic acid, triethyl ester, unii-9uvm48bas9, 9uvm48bas9, 1,1,1-triethoxypropan
• PubChem CID: 66995
• IUPAC Name: 1,1,1-triethoxypropane
• SMILES: CCOC(CC)(OCC)OCC

• Density: 0.88
• Boiling Point: 158°C
• Flash Point: 45°C (113°F)
• Odor: Slightly Sweetish
• Refractive Index: 1.402
• Linear Formula: CH₃CH₂C(OCH₂CH₃)₃
• Quantity: 500 mL
• UN Number: UN3272
• Beilstein: 906798
• Solubility Information: Hydrolyzes slowly in water. Soluble in alcohol,chloroform,ethyl acetate and ether.
• Formula Weight: 176.26
• Percent Purity: 98%
• Chemical Name or Material: Triethyl orthopropionate

Safety and Handling

Hazard Category	H226-H315-H319
Hazard Statement	GHS H Statement H226-H315-H319-H335 Flammable liquid and vapor. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P210-P233-P240-P241-P242-P243-P264b-P280-P303+P361+P353-P305+P351+P338-P332+P313-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: ESTERS, N.O.S.
EINECSNumber	204-108-0
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only