Triethyl phosphonoacetate, 98+%

Description

CAS: 867-13-0 | C8H17O5P | 224.193 g/mol

Triethyl phosphonoacetate serves as a reactant used in Horner-Wadsworth-Emmons reactions, Tsuji-Trost type reactions, Intramolecular Heck-type cyclization and isomerizations and Intramolecular aryne-ene reactions. In Horner-Wadsworth-Emmons reaction, it is utilized as a reagent to prepare chiral 2-methylcyclopropanecarboxylic acid from (S)-propylene oxide.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Triethyl phosphonoacetate serves as a reactant used in Horner-Wadsworth-Emmons reactions, Tsuji-Trost type reactions, Intramolecular Heck-type cyclization and isomerizations and Intramolecular aryne-ene reactions. In Horner-Wadsworth-Emmons reaction, it is utilized as a reagent to prepare chiral 2-methylcyclopropanecarboxylic acid from (S)-propylene oxide.

Solubility
Slightly miscible with water.

Notes
Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 867-13-0
• Molecular Formula: C8H17O5P
• Molecular Weight (g/mol): 224.193
• MDL Number: MFCD00009177
• InChI Key: GGUBFICZYGKNTD-UHFFFAOYSA-N
• Synonym: triethyl phosphonoacetate, ethyl 2-diethoxyphosphoryl acetate, ethyl diethoxyphosphoryl acetate, ethyl diethylphosphono acetate, triethyl phosphonoethanoate, diethyl carboethoxymethylphosphonate, diethyl ethoxycarbonylmethanephosphonate, diethylphosphonoacetic acid ethyl ester, diethyl carbethoxymethylphosphonate
• PubChem CID: 13345
• IUPAC Name: ethyl 2-diethoxyphosphorylacetate
• SMILES: CCOC(=O)CP(=O)(OCC)OCC

• Melting Point: -24°C
• Density: 1.125
• Boiling Point: 260°C to 262°C
• Flash Point: 165°C (329°F)
• Refractive Index: 1.431
• Quantity: 100 g
• Beilstein: 1343714
• Solubility Information: Slightly miscible with water.
• Formula Weight: 224.19
• Percent Purity: ≥98%
• Chemical Name or Material: Triethyl phosphonoacetate

Safety and Handling

Hazard Category	H315-H318-H335
Hazard Statement	GHS H Statement H315-H319 Causes skin irritation. Causes serious eye irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P312-P332+P313-P362-P501c
EINECSNumber	212-757-6
RTECSNumber	AG9800000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only