Trifluoroacetaldehyde hydrate, tech., ca 75% in water

Description

CAS: 421-53-4 | C2HF3O | 98.02 g/mol

One general application of trifluoroacetaldehyde is the preparation of trifluoroethylamino derivatives via reductive amination reaction. This synthesis includes the formation of the corresponding N,O-acetal intermediates followed by their reduction using NaBH4 or 2-picoline borane complex, affording the target trifluoroethylamino compounds in moderate to good yields. Another general application of trifluoroacetaldehyde is the synthesis of chiral α-substituted trifluoroethylamino compounds.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
One general application of trifluoroacetaldehyde is the preparation of trifluoroethylamino derivatives via reductive amination reaction. This synthesis includes the formation of the corresponding N,O-acetal intermediates followed by their reduction using NaBH4 or 2-picoline borane complex, affording the target trifluoroethylamino compounds in moderate to good yields. Another general application of trifluoroacetaldehyde is the synthesis of chiral α-substituted trifluoroethylamino compounds.

Solubility
Soluble in water.

Notes
Store at room temperature. Incompatible with oxidizing agents. Keep in cool place.

Specifications

Chemical Identifiers

• CAS: 421-53-4
• Molecular Formula: C2HF3O
• Molecular Weight (g/mol): 98.02
• MDL Number: MFCD00042444
• InChI Key: JVTSHOJDBRTPHD-UHFFFAOYSA-N
• Synonym: tfaih, fluoral hydrate, 1,1-ethanediol, 2,2,2-trifluoro, fluoral, hydrate, 2,2,2-trifluoro-1,1-ethanediol, acetaldehyde, trifluoro-, hydrate, 2,2,2-trifluoroethanediol, fluoral hydrate;, snpljqhjptadtaeup@, acetaldehyde, hydrate
• PubChem CID: 67901
• IUPAC Name: 2,2,2-trifluoroethane-1,1-diol
• SMILES: FC(F)(F)C=O

• Density: 1.44
• Boiling Point: 104°C to 106°C
• Flash Point: None
• Linear Formula: CF₃CH(OH)₂
• Quantity: 10 g
• UN Number: UN1989
• Solubility Information: Soluble in water.
• Formula Weight: 116.04 (Anhydrous)
• Percent Purity: 75%
• Grade: Technical
• Concentration or Composition (by Analyte or Components): ≈75% in water
• Chemical Name or Material: Trifluoroacetaldehyde hydrate

Safety and Handling

Hazard Category	H225-H302-H315-H317-H318-H335
Hazard Statement	GHS H Statement H225-H318-H302-H317-H335-H315 Highly flammable liquid and vapour. Causes serious eye damage. Harmful if swallowed. May cause an allergic skin reaction. May cause respiratory irritation. Causes skin irritation.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P261-P264b-P270-P271-P272-P280-P301+P312-P303+P361+P353-P304+P340-P305+P351+P338-P310-P312-P330-P333+P313-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: ALDEHYDES, N.O.S.
EINECSNumber	207-006-4
RTECSNumber	KI2850000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only