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Invitrogen™ TRIM Monoclonal Antibody (TRIM-04)
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Catalog No. 01676039
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100 μg
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Catalog No. Quantity
01-676-039 100 μg
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Catalog No. 01-676-039 Supplier Invitrogen™ Supplier No. MA119283
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Description

Mouse Monoclonal Antibody

This antibody recognizes an intracellular epitope of T cell receptor-interacting molecule (TRIM), a 30 kDa adaptor protein expressed by T cells. This antibody will not cross-react with mouse. Western Blot: non-reducing conditions.

TRIM (T cell receptor-interacting molecule), also known as TRAT1 (T cell receptor associated transmembrane adaptor 1) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear.
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Specifications

Antigen TRIM
Applications Flow Cytometry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone TRIM-04
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene TRAT1
Gene Accession No. Q6PIZ9
Gene Alias C030046M14Rik; HSPC062; pp29/30; T cell receptor associated transmembrane adaptor 1; T cell receptor interacting molecule; T-cell receptor interacting molecule; T-cell receptor-associated transmembrane adapter 1; T-cell receptor-interacting molecule; TCRIM; Trat1; TRIM
Gene Symbols TRAT1
Host Species Mouse
Immunogen Recombinant intracellular domain (aa 29-186) of human TRIM.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50852
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG2a
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