Invitrogen™ TRIM Monoclonal Antibody (TRIM-04)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA119283

Catalog No. 01-676-039

Description

This antibody recognizes an intracellular epitope of T cell receptor-interacting molecule (TRIM), a 30 kDa adaptor protein expressed by T cells. This antibody will not cross-react with mouse. Western Blot: non-reducing conditions.

TRIM (T cell receptor-interacting molecule), also known as TRAT1 (T cell receptor associated transmembrane adaptor 1) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear.

Specifications

• Antigen: TRIM
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: Q6PIZ9
• Gene Symbols: TRAT1
• Immunogen: Recombinant intracellular domain (aa 29-186) of human TRIM.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Immunoprecipitation, Western Blot
• Clone: TRIM-04
• Conjugate: Unconjugated
• Gene: TRAT1
• Gene Alias: C030046M14Rik; HSPC062; pp29/30; T cell receptor associated transmembrane adaptor 1; T cell receptor interacting molecule; T-cell receptor interacting molecule; T-cell receptor-associated transmembrane adapter 1; T-cell receptor-interacting molecule; TCRIM; Trat1; TRIM
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 50852
• Content And Storage: 4°C, do not freeze
• Form: Liquid