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  6. Invitrogen™ TRIM21 Recombinant Human Monoclonal Antibody (K52008_20G7) 

Invitrogen™ TRIM21 Recombinant Human Monoclonal Antibody (K52008_20G7)
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Catalog No. MA563050
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MA563050 100 μL
MA564509 50 μL
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Catalog No. MA563050 Supplier Invitrogen™ Supplier No. MA563050
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Description

Human Recombinant Monoclonal Antibody

Immunogen sequence: QEAREGTQGE RCAVHGERLH LFCEKDGKAL CWVCAQSRKH RDHAMVPLEE AAQEYQEKLQ VALGELRRKQ ELAEKLEVEI AIKRADWKKT VETQKSRIHA EFVQQKNFLV EEEQRQLQEL EKDEREQLRI LGEKEAKLAQ QSQALQELIS ELDRRCHSSA LELLQEVIIV LERSESWNLK Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 36%, Pig - 74%, Cynomolgus monkey - 92%.

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRIM21
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone K52008_20G7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene TRIM21
Gene Accession No. P19474
Gene Alias 52 kDa ribonucleoprotein autoantigen Ro/SS-A; 52 kDa Ro protein; 52kD Ro/SSA autoantigen; E3 ubiquitin-protein ligase TRIM21; RING finger protein 81; RING-type E3 ubiquitin transferase TRIM21; RNF81; Ro(SS-A); Ro/SSA; RO52; Sicca syndrome antigen A; sjoegren syndrome type A antigen; Sjogren syndrome antigen A1; Sjogren syndrome antigen A1 (52kDa, ribonucleoprotein autoantigen SS-A/Ro); SSA; SS-A; Ssa1; TRIM21; tripartite motif containing 21; tripartite motif protein 21; tripartite motif-containing 21; tripartite motif-containing protein 21
Gene Symbols TRIM21
Host Species Human
Immunogen Recombinant human TRIM21 (aa 81-260).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6737
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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