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Invitrogen™ TRIM21 Recombinant Rabbit Monoclonal Antibody (PSH02-56)
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Catalog No. MA552082
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MA552082 100 μL
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Catalog No. MA552082 Supplier Invitrogen™ Supplier No. MA552082
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Description

Rabbit Recombinant Monoclonal Antibody

Tissue Specificity: fetal and adult heart and fetal lung. Positive Control: HeLa cell lysate, HeLa treated with 10 ng/mL IFN-alpha for 16 hours cell lysate, A549 cell lysate, 293T cell lysate, U-2 OS cell lysate, U-2 OS, human spleen tissue, human tonsil tissue. Subcellular Location: Cytoplasm, Cytoplasmic vesicle, autophagosome, Nucleus, P-body. Predicted band size: 54 kDa.

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.
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Specifications

Antigen TRIM21
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone PSH02-56
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene TRIM21
Gene Accession No. P19474
Gene Alias 52 kDa ribonucleoprotein autoantigen Ro/SS-A; 52 kDa Ro protein; 52kD Ro/SSA autoantigen; E3 ubiquitin-protein ligase TRIM21; RING finger protein 81; RING-type E3 ubiquitin transferase TRIM21; RNF81; Ro(SS-A); Ro/SSA; RO52; Sicca syndrome antigen A; sjoegren syndrome type A antigen; Sjogren syndrome antigen A1; Sjogren syndrome antigen A1 (52kDa, ribonucleoprotein autoantigen SS-A/Ro); SSA; SS-A; Ssa1; TRIM21; tripartite motif containing 21; tripartite motif protein 21; tripartite motif-containing 21; tripartite motif-containing protein 21
Gene Symbols TRIM21
Host Species Rabbit
Immunogen Recombinant protein within human TRIM21 aa 1-475.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6737
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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