Invitrogen™ TRIM67 Polyclonal Antibody

Catalog No.	Quantity
PIPA5144056	100 μg

Catalog No. PIPA5144056 Supplier Invitrogen™ Supplier No. PA5144056

Description

Rabbit Polyclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human HepG2 whole cell, human A549 whole cell, human Caco-2 whole cell, rat C6 whole cell. Flow: HEL cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The TRIM67 gene encodes a member of the tripartite motif (TRIM) protein family, which is involved in various cellular processes including protein ubiquitination, signal transduction, and immune responses. TRIM67 contains RING, B-box, and coiled-coil domains, characteristic of TRIM proteins, which facilitate interactions with other proteins and contribute to its role in ubiquitination and cellular regulation. TRIM67 is notably expressed in the brain and has been associated with neurodevelopmental processes, particularly influencing neuronal differentiation and synapse formation. This gene plays a regulatory role in signaling pathways that are critical for neural development, and mutations or dysregulation in TRIM67 have been linked to neurodevelopmental disorders and cognitive deficits. Additionally, TRIM67's involvement in protein degradation and signal modulation may impact cellular architecture and brain function. Ongoing research seeks to elucidate TRIM67's precise mechanisms and potential therapeutic targets for neurological conditions.

Specifications

• Antigen: TRIM67
• Applications: ELISA, Flow Cytometry, Western Blot
• Classification: Polyclonal
• Concentration: 500 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 4mg trehalose and no preservative
• Gene: TRIM67
• Gene Accession No.: Q6ZTA4
• Gene Alias: D130049O21Rik; RGD1560667; TNL; Trim67; TRIM9-like protein; TRIM9-like protein TNL; tripartite motif containing 67; tripartite motif-containing 67; tripartite motif-containing protein 67
• Gene Symbols: TRIM67
• Host Species: Rabbit
• Immunogen: E.coli-derived human TRIM67 recombinant protein (Position: H24-D545).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 307938, 440730
• Target Species: Human, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG