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Invitrogen™ TrkA Polyclonal Antibody
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Catalog No. PIPA5109216
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100 μL
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PIPA5109216 100 μL
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Catalog No. PIPA5109216 Supplier Invitrogen™ Supplier No. PA5109216
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Description

Rabbit Polyclonal Antibody

Positive Control: SHSY5Y, SHG-44, PC-12, Human liver cancer tissue, human stomach cancer tissue, mouse brain tissue, rat brain tissue.

NTRK1 (TRKA) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TrkA
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.2% BSA and 0.05% sodium azide; pH 7.4
Gene Ntrk1
Gene Accession No. P04629
Gene Alias C80751; DKFZp781I14186; EC 2.7.10.1; gp140trk; high affinity nerve growth factor receptor; kinase TrkA; MTC; neurotrophic receptor tyrosine kinase 1; Neurotrophic tyrosine kinase receptor type 1; neurotrophic tyrosine kinase, receptor, type 1; Ntrk1; Oncogene TRK; p140-TrkA; Slow nerve growth factor receptor; Tkr; TRK; TRK1; TRK1-transforming tyrosine kinase protein; Trka; Trk-A; TrkA neurotrophin receptor; trkA proto-oncogene receptor; tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A
Gene Symbols Ntrk1
Host Species Rabbit
Immunogen Recombinant protein within Human TrkA aa 520-796.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4914
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles, store in dark
Product Type Antibody
Form Liquid
Isotype IgG
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