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TRPC5 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501735117 Shop All Proteintech Group Inc Products
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50-173-5117 150 μL
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Catalog No. 50-173-5117 Supplier Proteintech Group Inc Supplier No. 258901AP150UL
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Description

Rabbit Polyclonal Antibody

TRPC5 belongs to the transient receptor family. TRPC5 is one of the seven mammalian TRPC (transient receptor potential channel) proteins. The TRPC5 protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC5 is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. TRPC5 also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1). TRPC5 is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC5 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, or G-protein coupled receptors. TRPC5 has also been shown to be calcium-selective, and may also be activated by intracellular calcium store depletion. Diseases associated with TRPC5 include Hypertrophic Pyloric Stenosis and Pyloric Stenosis.

Specifications

Antigen TRPC5
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene TRPC5
Gene Accession No. Q9QX29, Q9UL62
Gene Alias hTRP 5, hTRP5, Transient receptor protein 5, TRP 5, TRP5, TRPC5
Gene Symbols TRPC5
Host Species Rabbit
Immunogen TRPC5 Fusion Protein Ag23171
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22067, 7224
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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