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Invitrogen™ TRPV2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA118351
Description
Reconstitute in 50 μL of sterile water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20 °C for a higher stability, and at 4 °C with an appropriate antibacterial agent.
VLR-1 is a calcium-permeable, non-selective cation channel with an outward rectification, that seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. VRL-1 does not respond to capsaicin, acid, or moderate heat, but instead is activated by high temperatures, with a threshold of approximately 52 degrees C. Within sensory ganglia, VRL-1 is most prominently expressed by a subset of medium- to large-diameter neurons, making it a candidate receptor for transducing high-threshold heat responses in this class of cells. VRL-1 transcripts are not restricted to the sensory nervous system, indicating that this channel may be activated by stimuli other than heat. VRL-1 is one of the six members of the vanilloid-like TRP-channel family which is now known as TRPV family.
Specifications
TRPV2 | |
Polyclonal | |
Unconjugated | |
Trpv2 | |
GRC; growth factor regulated channel; growth factor-regulated calcium channel; Osm-9-like TRP channel 2; OTRPC2; RP23-234K24.7; Sac2b; Stretch-activated channel 2B; transient receptor potential cation channel subfamily V member 2; transient receptor potential cation channel, subfamily V, member 2; Trpv2; Vanilloid receptor-like protein 1; VRL; Vrl1; VRL-1 | |
Rabbit | |
Affinity chromatography | |
RUO | |
29465, 51393 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunohistochemistry (Frozen), Western Blot | |
1 mg/mL | |
PBS with 0.02% sodium azide | |
Q9WUD2, Q9Y5S1 | |
Trpv2 | |
Synthetic peptide corresponding to residues C-K(744) N S A S E E D H L P L Q V L Q S P(761) of rat VRL-1. | |
50 μg | |
Primary | |
Human, Rat | |
Antibody | |
IgG |
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