Invitrogen™ TRPV3 Monoclonal Antibody (N15/4), APC

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA545427

Catalog No. PIMA545427

Description

1 μg/mL of MA5-45427 was sufficient for detection of TrpV3 in 10 μg of COS-1 cell lysate transiently transfected with TrpV3 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 70kDa.

TRPV3 belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels.

Specifications

• Antigen: TRPV3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4
• Gene Accession No.: Q8K424, Q8NET8
• Gene Symbols: TRPV3
• Immunogen: Synthetic peptide amino acids 774-791 (C-terminus) of rat TrpV3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Microarray
• Clone: N15/4
• Conjugate: APC
• Gene: TRPV3
• Gene Alias: 1110036I10Rik; AI644701; FNEPPK2; heat sensitive channel TRPV3; MGC124324; MGC124325; Nh; non-hair; OLMS; Transient receptor potential cation channel subfamily V member 3; transient receptor potential cation channel, subfamily V, member 3; TRP ion channel TRPV3; TrpV3; Vanilloid receptor-like 3; vanilloid receptor-related osmotically activated channel protein; VRL 3; VRL3; VRL-3
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 162514, 246788, 497948
• Content And Storage: 4°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov