TSHZ1 Monoclonal Antibody (OTI8A9), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA809993

Catalog No. 50-168-3142

Description

The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. TSHZ1 has been found to be required for axial skeleton, soft palate and middle ear development in mice and may be involved in a common pathway with the Hox genes. Both TSHZ1 and the related protein TSHZ3 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4.

Specifications

• Antigen: TSHZ1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q6ZSZ6
• Gene Symbols: TSHZ1
• Immunogen: Human recombit protein fragment corresponding to amino acids 29-176 of human TSHZ1 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI8A9
• Conjugate: Unconjugated
• Gene: TSHZ1
• Gene Alias: CAA, NY-CO-33, SDCCAG33, TSH1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10194
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid