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  6. Invitrogen™ TSLP Receptor Monoclonal Antibody (eBio1A6 (1A6)), Super Bright™ 436, eBioscience™, Invitrogen™ 

Invitrogen™ TSLP Receptor Monoclonal Antibody (eBio1A6 (1A6)), Super Bright™ 436, eBioscience™, Invitrogen™
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Catalog No. 62549942
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62-549-942 100 Tests
62-549-941 25 Tests
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Catalog No. 62-549-942 Supplier Invitrogen™ Supplier No. 62549942
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Description

Mouse Monoclonal Antibody

Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Its receptor TSLP-R will bind TSLP in a low-affinity fashion in transfected cells; co-transfection with IL-7R-alpha cDNA results in high-affinity binding and a functional heteromeric complex. This heteromeric receptor requires stat5 for TSLP-mediated signal transduction and is inhibited by SOCS-1.
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Specifications

Antigen TSLP Receptor
Applications Flow Cytometry
Classification Monoclonal
Clone eBio1A6 (1A6)
Concentration 5 μL/Test
Conjugate Super Bright 436
Formulation PBS with BSA and 0.09% sodium azide; pH 7.2
Gene CRLF2
Gene Accession No. Q9HC73
Gene Alias CRL2; Crlf2; CRLF2Y; Crlm2; CRLM-2; cytokine receptor CRL2 precusor; Cytokine receptor-like 2; Cytokine receptor-like factor 2; cytokine receptor-like molecule 2; delta 1; ILXR; IL-XR; Ly114; lymphocyte antigen 114; P2RY8/CRLF2 fusion; thymic stromal lymphopoietin protein receptor; thymic stromal-derived lymphopoietin receptor; thymic stromal-derived lymphopoietin, receptor; Tpte2; transmembrane phosphoinositide 3-phosphatase and tensin homolog 2; TSLP receptor; Tslpr; type I cytokine receptor delta 1; WI2-87105E3.1
Gene Symbols CRLF2
Host Species Mouse
Purification Method Affinity chromatography
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64109
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a λ
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