TSN Monoclonal Antibody (OTI1B5), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA809099

Catalog No. 50-168-2562

Description

Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.

Specifications

• Antigen: TSN
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: TSN
• Gene Alias: BCLF-1, C3PO, RCHF1, REHF-1, TBRBP, TRSLN
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7247
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1B5
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q15631
• Gene Symbols: TSN
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-51 of human TSN produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a