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Invitrogen™ TTR Monoclonal Antibody (2E10C5)
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Catalog No. PIMA1221
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100 μg
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Catalog No. Quantity
PIMA1221 100 μg
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Catalog No. PIMA1221 Supplier Invitrogen™ Supplier No. MA1221
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Description

Mouse Monoclonal Antibody

MA1-221 detects Transthyretin protein in ELISA and Western Blot applications. The MA1-221 immunogen is the purified recombinant fragment of human TTR (AA: 1-147) expressed in E. Coli.

Transthyretin (TTR), generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TTR
Applications ELISA, Western Blot
Classification Monoclonal
Clone 2E10C5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene TTR
Gene Accession No. P02766
Gene Alias AA408768; AI787086; Amyloidosis I; ATTR; carpal tunnel syndrome 1; CTS; CTS1; D17860; epididymis luminal protein 111; HEL111; HsT2651; Lr1; PALB; prealbumin; pre-albumin; prealbumin, amyloidosis type I; Tbpa; thyroxine-binding prealbumin; transthyretin; Tt; TTR
Gene Symbols TTR
Host Species Mouse
Immunogen Purified recombinant fragment of human TTR (AA: 1-147) expressed in E. Coli.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7276
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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