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Invitrogen™ TTYH2 Polyclonal Antibody
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Catalog No. PIPA534395
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100 μg
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Catalog No. Quantity
PIPA534395 100 μg
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Catalog No. PIPA534395 Supplier Invitrogen™ Supplier No. PA534395
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Rabbit Polyclonal Antibody

A suggested positive control is human kidney tissue lysate. PA5-34395 can be used with blocking peptide PEP-1437.

TTYH2 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH2 is a Ca2+-activated large conductance chloride (Cl-) channel and may play a role in kidney tumorigenesis. It is also upregulated in colon carcinoma and is thought to play a role in cell proliferation and call aggregation, suggesting that TTYH2 may play a role in regulating both proliferation and metastatic potentials of colorectal cancer. The ubiquitin-protein ligase Nedd4-2 binds to and ubiquitinates TTYH2, thereby regulating its cell surface expression and total cellular levels.
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Specifications

Antigen TTYH2
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene TTYH2
Gene Accession No. Q3TH73, Q9BSA4
Gene Alias 1110001A03Rik; C17orf29; hTTY2; mTTY2; Protein tweety homolog 2; RGD1562969; TTYH2; tweety family member 2; tweety homolog 2; tweety homolog 2 (Drosophila)
Gene Symbols TTYH2
Host Species Rabbit
Immunogen A 14 amino acid synthetic peptide near the amino terminus of human TTYH2.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117160, 287803, 94015
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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