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  6. Invitrogen™ TWIST1 Recombinant Rabbit Monoclonal Antibody (BLR156J)

Invitrogen™ TWIST1 Recombinant Rabbit Monoclonal Antibody (BLR156J)
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Catalog No. PIMA544497
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100 μL
Catalog No. Quantity
PIMA544497 100 μL
PIMA544498 10 μL
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Catalog No. PIMA544497

Supplier: Invitrogen™ MA544497

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Description

Rabbit Recombinant Monoclonal Antibody

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

TWIST1 acts as a transcriptional regulator. It inhibits myogensis by sequestering E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. TWIST1 also represses proinflammatory cytokines such as TNFA and IL1B. TWIST also regulates cranial suture patterning and fusion and gene expression differentially depending on dimer composition. Mutations in the gene are implicated in Saethre-Chotzen syndrome, a disease characterized by coronal synostosis, brachycephaly, low front hairline, facial asymmetry, hypertelorism, broad halluces, and clinodactyly.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TWIST1
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone BLR156J
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 6.8-7.4
Gene TWIST1
Gene Accession No. Q15672
Gene Alias AA960487; ACS3; B-HLH DNA binding protein; bHLHa38; BPES2; BPES3; charlie chaplin; class A basic helix-loop-helix protein 38; CRS; CRS1; CSO; H-twist; M-twist; p ACS3; Pde; pdt; Pluridigite; polydactyly EMS; SCS; Ska>m10Jus>; Ska>sup>m10Jus>/sup>; Ska10; Twist; twist basic helix-loop-helix transcription factor 1; twist family bHLH transcription factor 1; twist gene homolog 1; twist homolog 1; TWIST homolog of drosophila; Twist1; twist-related protein 1
Gene Symbols TWIST1
Host Species Rabbit
Immunogen Peptide representing a region between residue 1 and 50 of Human Twist-related protein 1.
Purification Method Purified
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7291
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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