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TWIST1 and TWIST2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Rabbit Polyclonal Antibody

Supplier:  Bioss BS2441R

Encompass_Preferred

Catalog No. 50-198-4731


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Description

Description

Twist1/Twist2 encodes a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. The encoded protein forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development. This protein may also regulate neural tube closure, limb development and brown fat metabolism. Twist1/Twist2 is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis. Mutations in this gene cause Saethre-Chotzen syndrome in human patients, which is characterized by craniosynostosis, ptosis and hypertelorism.
Specifications

Specifications

TWIST1 and TWIST2
Polyclonal
Unconjugated
TWIST2
AA960487; ACS3; AMS; BBRSAY; B-HLH DNA binding protein; BHLHA38; BHLHA39; BPES2; BPES3; charlie chaplin; Class A basic helix-loop-helix protein 38; Class A basic helix-loop-helix protein 39; CRS; CRS1; CSO; dermis expressed 1; Dermis-expressed protein 1; DERMO1; Dermo-1; dermo-1 protein; FFDD3; H-twist; MGC117334; M-twist; Pde; pdt; Pluridigite; polydactyly EMS; SCS; SETLSS; Ska; Skam10Jus; Ska10; Twist; twist basic helix-loop-helix transcription factor 1; twist basic helix-loop-helix transcription factor 2; twist family bHLH transcription factor 1; twist family bHLH transcription factor 2; twist gene homolog 1; twist homolog 1; twist homolog 2; TWIST homolog of drosophila; Twist1; Twist2; twist-related bHLH protein Dermo1; Twist-related protein 1; Twist-related protein 2
Rabbit
Protein A
RUO
117581, 7291
-20°C
Liquid
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Q15672, Q8WVJ9
TWIST1, TWIST2
KLH conjugated synthetic peptide derived from human TWIST1.
100 μL
Primary
Human
Antibody
IgG
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