TXNRD1 Monoclonal Antibody (OTI3E1), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA811364

Catalog No. 50-168-3994

Description

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3′ UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

Specifications

• Antigen: TXNRD1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O89049, Q16881, Q9JMH6
• Gene Symbols: Txnrd1
• Immunogen: Full length human recombit protein of human TXNRD1 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI3E1
• Conjugate: Unconjugated
• Gene: TXNRD1
• Gene Alias: GRIM-12, TR, TR1, TRXR1, TXNR
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 50493, 58819, 7296
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid