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Invitrogen™ TYRO3 Polyclonal Antibody
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Catalog No. PIPA5110535
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100 μL
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PIPA5110535 100 μL
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Catalog No. PIPA5110535 Supplier Invitrogen™ Supplier No. PA5110535
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PATNYSLRVR CANALGPSPY ADWVPFQTKG LAPASAPQNL HAIRTDSGLI LEWEEVIPEA PLEGPLGPYK LSWVQDNGTQ DELTVEGTRA NLTGWDPQKD LIVRVCVSNA VGCGPWSQPL VVSSHDRAGQ QGPPHSRTSW V.

TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. It regulates many physiological processes including cell survival, migration, and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by a ligand, TYRO3 plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation, signal transduction, cell adhesion. and cytoskeleton reorganization.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TYRO3
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.87 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene TYRO3
Gene Accession No. P55144, P55146
Gene Alias AI323366; Brt; Bruton agammaglobulinemia tyrosine kinase; BYK; Dtk; Etk-2; etk2/tyro3; FLJ16467; Rek; Rse; Sky; soluble tyro 3; soluble tyro3; styro 3; styro3; TIF; TK19-2; tyro 3; TYRO3; TYRO3 protein tyrosine kinase; TYRO3 protein tyrosine kinase 3; tyrosine-protein kinase byk; Tyrosine-protein kinase DTK; tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase RSE; tyrosine-protein kinase SKY; Tyrosine-protein kinase TIF
Gene Symbols TYRO3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 290-430 of human TYRO3 (NP_006284.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22174, 25232
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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