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Invitrogen™ TYRO3 Recombinant Rabbit Monoclonal Antibody (14H68L59)

Catalog No. 703554
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70-355-4 100 μg
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Catalog No. 70-355-4 Supplier Invitrogen™ Supplier No. 703554
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Pig, Bovine, Cat. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. It regulates many physiological processes including cell survival, migration, and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by a ligand, TYRO3 plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation, signal transduction, cell adhesion. and cytoskeleton reorganization.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TYRO3
Applications Western Blot
Classification Recombinant Monoclonal
Clone 14H68L59
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene TYRO3
Gene Accession No. P55144, P55146, Q06418
Gene Alias AI323366; Brt; Bruton agammaglobulinemia tyrosine kinase; BYK; Dtk; Etk-2; etk2/tyro3; FLJ16467; Rek; Rse; Sky; soluble tyro 3; soluble tyro3; styro 3; styro3; TIF; TK19-2; tyro 3; TYRO3; TYRO3 protein tyrosine kinase; TYRO3 protein tyrosine kinase 3; tyrosine-protein kinase byk; Tyrosine-protein kinase DTK; tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase RSE; tyrosine-protein kinase SKY; Tyrosine-protein kinase TIF
Gene Symbols TYRO3
Host Species Rabbit
Immunogen Protein corresponding to human TYRO3 [aa790-aa890].
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22174, 25232, 7301
Target Species Human, Mouse, Rat, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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