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Invitrogen™ TYROBP Polyclonal Antibody
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Catalog No. PIPA583577
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100 μL
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PIPA583577 100 μL
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Catalog No. PIPA583577 Supplier Invitrogen™ Supplier No. PA583577
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: FLGRLVPRGR GAAEAATRKQ RITETESPYQ ELQGQRSDVY SDLNTQRPYY K Highest antigen sequence indentity to the following orthologs: Mouse - 76%, Rat - 75%.

DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TYROBP
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TYROBP
Gene Accession No. O43914
Gene Alias DAP12; DNAX-activation protein 12; KARAP; KAR-associated protein; killer cell activating receptor associated protein; killer cell activating receptor-associated protein; killer-activating receptor-associated protein; Ly83; PLOSL; TYRO protein tyrosine kinase binding protein; TYRO protein tyrosine kinase-binding protein; Tyrobp
Gene Symbols TYROBP
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TYROBP. Recombinant protein control fragment (Product #RP-98856).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7305
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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