Invitrogen™ Tyrosinase Monoclonal Antibody (T311)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA514177

Catalog No. PIMA514177

Description

MA5-14177 targets Tyrosinase in ICC, IF, IHC (P), and WB applications and shows reactivity with Human samples. The MA5-14177 immunogen is recombinant tyrosinase protein.

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.

Specifications

• Antigen: Tyrosinase
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Formulation: PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P11344, P14679
• Gene Symbols: TYR
• Immunogen: Recombinant tyrosinase protein.
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: T311
• Conjugate: Unconjugated
• Gene: TYR
• Gene Alias: albino; albino locus protein; ATN; C; CMM8; LB24-AB; monophenol monooxygenase; Oca1; OCA1A; OCAIA; oculocutaneous albinism IA; SHEP3; SK29-AB; skc35; Tumor rejection antigen AB; TYR; Tyrosinase; tyrosinase (oculocutaneous albinism IA); tyrosinase precursor
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 22173, 7299
• Content And Storage: 4°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov