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Invitrogen™ Tyrosinase Monoclonal Antibody (T311)
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Catalog No. PIMA514177
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500 μL
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PIMA514177 500 μL
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Catalog No. PIMA514177 Supplier Invitrogen™ Supplier No. MA514177
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Description

Mouse Monoclonal Antibody

MA5-14177 targets Tyrosinase in ICC, IF, IHC (P), and WB applications and shows reactivity with Human samples. The MA5-14177 immunogen is recombinant tyrosinase protein.

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Tyrosinase
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone T311
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene TYR
Gene Accession No. P11344, P14679
Gene Alias albino; albino locus protein; ATN; C; CMM8; LB24-AB; monophenol monooxygenase; Oca1; OCA1A; OCAIA; oculocutaneous albinism IA; SHEP3; SK29-AB; skc35; Tumor rejection antigen AB; TYR; Tyrosinase; tyrosinase (oculocutaneous albinism IA); tyrosinase precursor
Gene Symbols TYR
Host Species Mouse
Immunogen Recombinant tyrosinase protein.
Purification Method Protein A/G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22173, 7299
Target Species Human, Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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