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Eurofins Discoverx U-18666A, 5 mg. (92-1094)
Supplier: Eurofins Discoverx 921094

U 18666A is a small molecule inhibitor of cholesterol transport from endosomes/lysosomes to the endoplasmic reticulum in a variety of cell types, including macrophages and sympathetic neurons. Also weakly inhibits hedgehog signaling. Implicated in multiple diseases including Neimann-Pick disease type C (NPC), Alzheimer's, cataracts, and atherosclerosis. Provided as 5 mg of dry powder. These highly purified, pre-validated control ligands have been used to qualify our InCELL Hunter, PathHunter and cAMP Hunter cell lines as well as our Assay Ready Kits. Ligands are conveniently supplied with a recommended reconstitution buffer. For detailed information and product-specific datasheet, visit www.discoverx.com/ligands.
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