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Tocris Bioscience™ U0126
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Catalog No. 11445
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25 mg
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Catalog No. Quantity
11-445 5 mg
11-442-5 25 mg
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Catalog No. 11-445 Supplier Tocris Bioscience™ Supplier No. 1144/5
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Description

Potent, selective inhibitor of MEK1 and 2

Potent and selective non-competitive inhibitor of MAP kinase kinase. Inhibits MEK-1 and MEK-2 (IC50 values of 0.07 and 0.06 μM respectively) with little or no effect on the activities of PKC, Abl, Raf, MEKK, ERK, JNK, MKK-3, MKK-4/SEK, MKK-6, Cdk2 or Cdk4. Brain penetrant. Helps maintain human pluripotent stem cells in undifferentiated state.

Negative Control also available.

Chemical Identifiers

CAS 109511-58-2
Molecular Formula C18H16N6S2

Specifications

Quantity 5 mg
Formula Weight 380.48
Purity >98%
Molecular Weight (g/mol) 380.49
Chemical Name or Material U0126

Safety and Handling

Recommended Storage Desiccate at +4°C
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