U2AF1L4 Monoclonal Antibody (OTI9C2), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA810432

Catalog No. 50-168-3388

Description

RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3′-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3′-splice site.

Specifications

• Antigen: U2AF1L4
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q8WU68
• Gene Symbols: U2AF1L4
• Immunogen: Full length human recombit protein of human U2AF1L4 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI9C2
• Conjugate: Unconjugated
• Gene: U2AF1L4
• Gene Alias: U2AF1-RS3, U2AF1L3, U2AF1L3V1, U2AF1RS3, U2af26
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 199746
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid