U2AF35 Mouse anti-Human, Clone: 2B7F11, Proteintech

Catalog No.	Quantity
50-173-6384	150 μL

Catalog No. 50-173-6384 Supplier Proteintech Group Inc Supplier No. 602891IG150UL

Description

Mouse Monoclonal Antibody

U2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder.

Specifications

• Antigen: U2AF35
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: 2B7F11
• Concentration: 1.11 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: U2AF1
• Gene Accession No.: Q01081
• Gene Alias: FP793, RN, RNU2AF1, U2AF1, U2AF35, U2AFBP
• Gene Symbols: U2AF1
• Host Species: Mouse
• Immunogen: U2AF35 Fusion Protein Ag0399
• Purification Method: Protein A
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7307
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2c