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Invitrogen™ UBE2C Monoclonal Antibody (1F5D3)
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Catalog No. MA1173 Shop All Thermo Scientific Products
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MA1173 100 μg
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Catalog No. MA1173 Supplier Invitrogen™ Supplier No. MA1173
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Description

Mouse Monoclonal Antibody

UBE2C Monoclonal Antibody for ICC/IF, Western Blot

This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE2C
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 1F5D3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 30% glycerol, 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene UBE2C
Gene Accession No. O00762, Q9D1C1
Gene Alias (E3-independent) E2 ubiquitin-conjugating enzyme C; 1110015A16Rik; cyclin-selective ubiquitin carrier protein; D2Ertd695e; dJ447F3.2; E2 ubiquitin-conjugating enzyme C; mitotic-specific ubiquitin-conjugating enzyme; RP3-447F3.1; ubcH10; UBE2C; Ubiquitin carrier protein C; ubiquitin conjugating enzyme E2 C; ubiquitin conjugating enzyme E2C; ubiquitin-conjugating enzyme E2 C; ubiquitin-conjugating enzyme E2C; ubiquitin-protein ligase C
Gene Symbols UBE2C
Host Species Mouse
Immunogen Recombinant full length protein corresponding to Human UBE2C aa 1-179.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11065, 296368, 485898, 68612
Target Species Canine, Human, Mouse, Monkey, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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