Invitrogen™ UBE2R2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110538

Catalog No. PIPA5110538

Description

Immunogen sequence: MAQQQMTSSQ KALMLELKSL QEEPVEGFRI TLVDESDLYN WEVAIFGPPN TLYEGGYFKA HIKFPIDYPY SPPTFRFLTK MWHPNIYENG DVCISILHPP VDDPQSGELP SERWNPTQNV RTILLSVISL LNEPNTFSPA NVDASVMFRK WRDSKGKDKE YAEIIRKQVS ATKAEAEKDG VKVPTTLAEY CIKTKVPSND NSSDLLYDDL YDDDIDDEDE EEEDADCYDD DDSGNEES.

Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.

Specifications

• Antigen: UBE2R2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UBE2R2
• Gene Alias: 1200003M11Rik; CDC34B; cell division cycle 34 homolog; E2 ubiquitin-conjugating enzyme R2; E2-CDC34B; LOC689226; similar to ubiquitin-conjugating enzyme E2R 2; UBC3B; Ube2r2; Ubiquitin carrier protein R2; ubiquitin conjugating enzyme E2 R2; ubiquitin conjugating enzyme E2R 2; ubiquitin-conjugating enzyme E2 R2; ubiquitin-conjugating enzyme E2-32k; ubiquitin-conjugating enzyme E2-CDC34B; ubiquitin-conjugating enzyme E2R 2; ubiquitin-conjugating enzyme UBC3B; ubiquitin-protein ligase R2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54926, 67615, 689226
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.26 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q6ZWZ2, Q712K3
• Gene Symbols: UBE2R2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-238 of human UBE2R2 (NP_060281.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG