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UBE2T Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501561197
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50-156-1197 100 μL
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Catalog No. 50-156-1197 Supplier Bethyl Laboratories, Inc Supplier No. A301874A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

UBE2T is involved in the covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3). UBE2T catalyzes the covalent attachment of ubiquitin to protein substrates. Functionally, UBE2T accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins, catalyzes monoubiquitination, is involved in mitomycin-C (MMC)-induced DNA repair, and catalyzES monoubiquitination of FANCD2, a key step in the DNA damage pathway. Defects in the UBE2T gene have been associated with Fanconi anemia of complementation group T.

Specifications

Antigen UBE2T
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/ml
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene UBE2T
Gene Accession No. Q9NPD8
Gene Alias UBE2T; HSPC150; PIG50; HSPC150 protein similar to ubiquitin-conjugating enzyme; ubiquitin conjugating enzyme; ubiquitin-conjugating enzyme E2T (putative); ubiquitin-conjugating enzyme E2T
Gene Symbols UBE2T
Host Species Rabbit
Immunogen Between 147 and 197
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29089
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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