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Invitrogen™ UBE4B Recombinant Rabbit Monoclonal Antibody (1D7K5)
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Catalog No. PIMA542592
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PIMA542592 100 μL
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Catalog No. PIMA542592 Supplier Invitrogen™ Supplier No. MA542592
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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: PC-12, SKOV3, NIH/3T3, K-562, Mouse liver, Mouse brain, Rat liver, Rat brain. Immunogen sequence: MEELSADEIR RRRLARLAGG QTSQPTTPLT SPQRENPPGP PIAASAPGPS QSLGLNVHNM TPATSPIGAS GVAHRSQSSE GVSSLSSSPS NSLETQSQSL.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B represents an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. UBE4B also the strongest candidate among the neuroblastoma tumor suppressors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE4B
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 1D7K5
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene UBE4B
Gene Accession No. O95155, Q9ES00
Gene Alias 4930551I19Rik; 4933406G05Rik; AU014668; D4Bwg0973e; E4; HDNB1; homologous to yeast UFD2; homozygously deleted in neuroblastoma 1; homozygously deleted in neuroblastoma-1; KIAA0684; mKIAA0684; RING-type E3 ubiquitin transferase E4 B; Ube4b; Ubiquitin conjugation factor E4 B; ubiquitin fusion degradation protein 2; ubiquitination factor E4B; ubiquitination factor E4B (homologous to yeast UFD2); ubiquitination factor E4B (UFD2 homolog, yeast); ubiquitination factor E4B, UFD2 homolog; ubiquitin-fusion degradation protein 2; UBOX3; UFD2; Ufd2a; UFD2A-III/UBE4B-III splice isoform; Ufd2p
Gene Symbols UBE4B
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBE4B (O95155).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10277, 298652, 63958
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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