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Invitrogen™ Ubiquilin 1 Polyclonal Antibody
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Catalog No. PA1759
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100 μg
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PA1759 100 μg
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Catalog No. PA1759 Supplier Invitrogen™ Supplier No. PA1759
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Description

Rabbit Polyclonal Antibody

PA1-759 detects ubiquilin from hamster cells. PA1-759 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~63 kDa protein representing ubiquilin from CHO cell extract. PA1-759 immunizing peptide corresponds to amino acids residues 2-18 from mouse ubiquilin.

PLIC1 is an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ubiquilin 1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Ubqln1
Gene Accession No. Q8R317, Q9UMX0
Gene Alias 1110046H03Rik; 1810030E05Rik; AU019746; C77538; D13Ertd372e; Da41; Dsk2; hPLIC-1; I79_020705; Plic1; PLIC-1; Protein linking IAP with cytoskeleton 1; testicular tissue protein Li 219; ubiquilin 1; ubiquilin-1; UBQLN1; UBQN; XDRP1
Gene Symbols Ubqln1
Host Species Rabbit
Immunogen Synthetic Peptide: A(2) E S A E S G G P P G A Q D S A A(18).
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100764107, 29979, 56085
Target Species Human, Mouse, Hamster
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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