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Tocris Bioscience™ UBP 296
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Catalog No. 207810
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20-781-0 10 mg
20-785-0 50 mg
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Description

Potent and selective kainate antagonist; selective for GluK1-containing receptors

Selective GluK1 (formally GluR5) subunit containing kainate receptor antagonist (apparent KD = 1.09 μM). Displays ∽ 90-fold selectivity over AMPA receptors and recombinant hGluK2 (formally hGluR6) and GluK5 (formally KA2) containing kainate receptors. Has little or no action at NMDA or group I mGlu receptors. Selectively blocks kainate receptor-mediated LTP induction in rat hippocampal mossy fibers.

Active Enantiomer also available.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Chemical Identifiers

CAS 745055-86-1
Molecular Formula C15H15N3O6

Specifications

Quantity 10 mg
Formula Weight 333.3
Purity >98%
Molecular Weight (g/mol) 333.3
Chemical Name or Material UBP 296

Safety and Handling

Recommended Storage Store at Room Temperature
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