UBTF (phospho S484) Rabbit anti-Human, Mouse, Rat, Polyclonal , Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human UBTF.

Supplier:  Abnova Corporation PAB29589

Catalog No. 89-956-830

Description

Upstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP (MIM 600075) and multiple TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human (Bell et al., 1988 [PubMed 3413483]). UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes (Jantzen et al., 1990 [PubMed 2330041]).[supplied by OMIM]

Specifications

• Antigen: UBTF (phospho S484)
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human UBTF.
• Formulation: In PBS (without Mg²⁺ and Ca²⁺), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Symbols: UBTF
• Immunogen: A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S484 of human UBTF.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: UBTF (phospho S484) polyclonal antibody detects endogenous levels of human UBTF only when phosphorylated at serine 484.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:100) Western Blot (1:500-1:3000) The optimal working dilution should be determined by the end user.
• Gene Alias: NOR-90/UBF
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7343
• Target Species: Human, Mouse, Rat
• Form: Liquid