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UBTF (phospho S484) Rabbit anti-Human, Mouse, Rat, Polyclonal , Abnova™

Catalog No. 89956830 Shop All Abnova Corporation Products
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89-956-830 100 μL
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Catalog No. 89-956-830 Supplier Abnova Corporation Supplier No. PAB29589
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Rabbit polyclonal antibody raised against synthetic phosphopeptide of human UBTF.

Upstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP (MIM 600075) and multiple TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human (Bell et al., 1988 [PubMed 3413483]). UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes (Jantzen et al., 1990 [PubMed 2330041]).[supplied by OMIM]

Specifications

Antigen UBTF (phospho S484)
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human UBTF.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:100) Western Blot (1:500-1:3000) The optimal working dilution should be determined by the end user.
Formulation In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Alias NOR-90/UBF
Gene Symbols UBTF
Host Species Rabbit
Immunogen A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S484 of human UBTF.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7343
Test Specificity UBTF (phospho S484) polyclonal antibody detects endogenous levels of human UBTF only when phosphorylated at serine 484.
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG
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