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  5. Tocris Bioscience™ UC 112

Tocris Bioscience™ UC 112

Catalog No. 525110
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Catalog No. Quantity
52-511-0 10 mg
52-515-0 50 mg
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Catalog No. 52-511-0 Supplier Tocris Bioscience™ Supplier No. 5251/10
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Description

IAP and XIAP inhibitor; antitumor

UC 112 is an iAP inhibitor (IC50 values from 0.7 - 3.4 μM); inhibits cell growth in multiple cancer cell lines and in a melanoma xenograft model in vivo. Also suppresses X-linked inhibitor of apoptosis protein (XIAP) and survivin levels. Inhibits the growth of P-glycoproteins and activates caspase-3/7 and caspase-9.

Specifications

Purity >98%
Quantity 10 mg
Product Type UC 112
Molecular Weight (g/mol) 348.44
Inhibitors UC 112

For Research Use Only

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