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UCL 2077, Tocris Bioscience™

Catalog No. 266110
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10 mg
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Catalog No. Quantity
26-611-0 10 mg
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Catalog No. 26-611-0 Supplier R&D Systems Supplier No. 2661/10
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Description

Slow afterhyperpolarization (sAHP) channel blocker; sub-type selective Kv channel effects

Slow afterhyperpolarization (sAHP) channel blocker; reduces sAHP in hippocampal slice preparations. Displays no effect on Ca2+ currents or the time course of sAHP/sIAHP. Exhibits potent inhibition of KCNQ1 and KCNQ2, but differential effects at other KCNQs. Rescues memory retrieval in dopamine β-hydroxylase knockout mice.

Chemical Identifiers

CAS 918311-87-2
Molecular Formula C25H22N2
Molecular Weight (g/mol) 350.47
MDL Number MFCD00585879
InChI Key PQFNWDHABGBCHB-UHFFFAOYSA-N
Synonym 3-triphenylmethylaminomethyl pyridine, pyridin-3-ylmethyl triphenylmethyl amine, n-trityl-3-pyridinemethanamine, 3-tribenzylaminomethyl pyridine, ucl hplc , solid, 1,1,1-triphenyl-n-pyridin-3-yl methyl methanamine
PubChem CID 24868317
IUPAC Name [(pyridin-3-yl)methyl](triphenylmethyl)amine
SMILES C(NC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)C1=CN=CC=C1

Specifications

Quantity 10 mg
Formula Weight 350.46
Percent Purity >99%
Chemical Name or Material UCL 2077

Safety and Handling

Recommended Storage Store at Room Temperature
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