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UCP3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501726565 Shop All Proteintech Group Inc Products
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50-172-6565 150 μL
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Catalog No. 50-172-6565 Supplier Proteintech Group Inc Supplier No. 107501AP150UL
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Description

Rabbit Polyclonal Antibody

The uncoupling protein UCP1 (formerly designated UCP) is an integral membrane protein unique to brown adipose tissue mitochondria. UCP1 forms a dimer that acts as a proton channel, which can uncouple oxidative phosphorylation by dissipating the electrochemical potential across the inner mitochondrial membrane. This process induces heat production in brown adipose tissue and is involved in regulation of body temperature and glucose metabolism. UCP2 is a structurally related protein that also uncouples mitochondrial respiration. It is more widely expressed in human and mouse tissues, including white adipose tissue and muscle, than is UCP1. UCP2 is thought to play a role in body weight regulation. An additional UCP family member, UCP3, is highly muscle specific and is possibly involved in the uncoupling of oxidative phosphorylation in skeletal muscle.

Specifications

Antigen UCP3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.29 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene UCP3
Gene Accession No. P55916, P56499, P56501
Gene Alias SLC25A9, UCP 3, UCP3
Gene Symbols UCP3
Host Species Rabbit
Immunogen UCP3 Fusion Protein Ag1134
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22229, 25708, 7352
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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